ROLE OF SEROLOGICAL DIAGNOSIS FOR TUBERCULOSIS
TUBERCULOSIS IS A MAJOR DISEASE OF HUMAN KIND AND IS STILL A MAJOR PROBLEM SPECIALLY FOR DEVELOPING WORLD. HOWEVER THERE IS STILL CERTAIN CONTROVERSY IN DIAGNOSIS MOSTLY DUE TO SEROLOGICAL TEST.
RECENTLY WORLD HEALTH ORGANISATION HAS CAME OUT WITH A POLICY STATEMENT ON USE OF SEROLOGICAL TEST FOR DIAGNOSIS OF TUBERCULOSIS
WHO HAS CLEARLY RECOMMENDED AGAIST THE USE OF THESE TESTS FOR DIAGNOSIS OF TUBERCULOSIS
THE DOCUMENT IN THEIR CONCLUSION MENTIONED THAT
"Commercial serological tests provide inconsistent and imprecise findings resulting in highly variable values for sensitivity and specificity. There is no evidence that existing commercial serological assays improve patient-important outcomes, and high proportions of false-positive and false-negative results adversely impact patient safety. Overall data quality was graded as very low and it is strongly recommended that these tests not be used for the diagnosis of pulmonary and extra-pulmonary TB"
FOR MORE DETAIL GO THROUGH THE ORIGINAL WHO DOCUMENT
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